Drug interactions
Glycopyrrolate + Rimantadine
Severity: Minor
Glycopyrrolate and Rimantadine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Rimantadine has some anticholinergic-type central and peripheral effects at higher exposures, and glycopyrrolate is a peripheral antimuscarinic. Additive anticholinergic effects such as dry mouth, constipation or urinary retention are theoretically possible but not well documented.
What this interaction means in plain words
Glycopyrrolate and Rimantadine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Glycopyrrolate belongs to Respiratory; Rimantadine belongs to Anti Virals.
Why it happens
Possible additive anticholinergic pharmacodynamic effects; the mechanism is not firmly established.
What to do
No routine change is needed; monitor older patients for constipation, urinary retention and dry mouth if both are used.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Rimantadine
Other interactions of Glycopyrrolate
- Glycopyrrolate + Potassium chloride Major
- Amitriptyline + Glycopyrrolate Moderate
- Atropine + Glycopyrrolate Moderate
- Bethanechol + Glycopyrrolate Moderate
- Chlorpromazine + Glycopyrrolate Moderate
- Clomipramine + Glycopyrrolate Moderate
Frequently asked questions
Can I take Glycopyrrolate with Rimantadine?
MediHelp rates the interaction as minor. Glycopyrrolate and Rimantadine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Rimantadine has some anticholinergic-type central and peripheral effects at higher exposures, and glycopyrrolate is a peripheral antimuscarinic. Additive anticholinergic effects such as dry mouth, constipation or urinary retention are theoretically possible but not well documented.
How serious is the interaction between Glycopyrrolate and Rimantadine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine change is needed; monitor older patients for constipation, urinary retention and dry mouth if both are used.
What other medicines interact with Rimantadine?
MediHelp also lists interactions of Rimantadine with, for example, Henbane, Atropine iv /, Glycopyrronium. The full list is on the Rimantadine page.
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