Drug interactions
Henbane + Tiotropium
Severity: Moderate
Henbane and Tiotropium: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Henbane contains hyoscyamine and scopolamine, which are antimuscarinic alkaloids that add to the effects of tiotropium. This may cause dry mouth, tachycardia, urinary retention, confusion and raised intraocular pressure.
What this interaction means in plain words
Henbane and Tiotropium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive muscarinic receptor antagonism.
What to do
Avoid combined use where possible; monitor for anticholinergic toxicity such as tachycardia and confusion.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Tiotropium
Frequently asked questions
Can I take Henbane with Tiotropium?
MediHelp rates the interaction as moderate. Henbane and Tiotropium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Henbane contains hyoscyamine and scopolamine, which are antimuscarinic alkaloids that add to the effects of tiotropium. This may cause dry mouth, tachycardia, urinary retention, confusion and raised intraocular pressure.
How serious is the interaction between Henbane and Tiotropium?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid combined use where possible; monitor for anticholinergic toxicity such as tachycardia and confusion.
What other medicines interact with Tiotropium?
MediHelp also lists interactions of Tiotropium with, for example, Glycopyrrolate inhaled, Indacaterol-glycopyrronium, Revefenacin. The full list is on the Tiotropium page.
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