Drug interactions
Heparin + Vitamin e
Severity: Minor
Heparin and Vitamin e: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
High-dose vitamin E may have mild antiplatelet effects and could slightly add to the bleeding tendency of heparin. At usual supplement doses, clinically meaningful effects are not expected.
What this interaction means in plain words
Heparin and Vitamin e have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Heparin belongs to Cardiovascular; Vitamin e belongs to Gastrointestinal Tract.
Why it happens
High-dose vitamin E may inhibit platelet aggregation and antagonize vitamin K-dependent clotting, a weak additive effect.
What to do
Avoid megadoses of vitamin E while on heparin. Monitor for bleeding if high-dose supplements are used.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Heparin
- Defibrotide + Heparin Contraindicated
- Heparin + Ketorolac Contraindicated
- Heparin + Oritavancin Contraindicated
- Acemetacin + Heparin Major
- Acetylsalicylic acid + Heparin Major
- Alteplase + Heparin Major
Other interactions of Vitamin e
- Betrixaban + Vitamin e Moderate
- Phenindione + Vitamin e Moderate
- Selumetinib + Vitamin e Moderate
- Vitamin e + Warfarin Moderate
- Alfalfa + Vitamin e Minor
- Antithrombin alfa + Vitamin e Minor
Frequently asked questions
Can I take Heparin with Vitamin e?
MediHelp rates the interaction as minor. Heparin and Vitamin e have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. High-dose vitamin E may have mild antiplatelet effects and could slightly add to the bleeding tendency of heparin. At usual supplement doses, clinically meaningful effects are not expected.
How serious is the interaction between Heparin and Vitamin e?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid megadoses of vitamin E while on heparin. Monitor for bleeding if high-dose supplements are used.
What other medicines interact with Heparin?
MediHelp also lists interactions of Heparin with, for example, Defibrotide, Ketorolac, Oritavancin. The full list is on the Heparin page.
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