Drug interactions
Hepatitis A vaccine inactivated + Onasemnogene abeparvovec
Severity: Minor
Hepatitis A vaccine inactivated and Onasemnogene abeparvovec: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Onasemnogene is given with corticosteroids that can reduce responses to vaccines. Inactivated vaccines are not contraindicated but immunogenicity may be reduced, so timing matters.
What this interaction means in plain words
Hepatitis A vaccine inactivated and Onasemnogene abeparvovec have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Hepatitis A vaccine inactivated belongs to Anti Virals; Onasemnogene abeparvovec belongs to Miscellaneous.
Why it happens
Concomitant corticosteroid immunosuppression may blunt antibody responses to vaccination.
What to do
Give inactivated vaccines at least 2 weeks before starting corticosteroid prophylaxis where feasible, and follow specialist guidance on scheduling.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Hepatitis A vaccine inactivated
- Adalimumab + Hepatitis A vaccine inactivated Moderate
- Alefacept + Hepatitis A vaccine inactivated Moderate
- Anakinra + Hepatitis A vaccine inactivated Moderate
- Anti-thymocyte + Hepatitis A vaccine inactivated Moderate
- Antithymocyte globulin equine + Hepatitis A vaccine inactivated Moderate
- Antithymocyte globulin rabbit + Hepatitis A vaccine inactivated Moderate
Other interactions of Onasemnogene abeparvovec
Frequently asked questions
Can I take Hepatitis A vaccine inactivated with Onasemnogene abeparvovec?
MediHelp rates the interaction as minor. Hepatitis A vaccine inactivated and Onasemnogene abeparvovec have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Onasemnogene is given with corticosteroids that can reduce responses to vaccines. Inactivated vaccines are not contraindicated but immunogenicity may be reduced, so timing matters.
How serious is the interaction between Hepatitis A vaccine inactivated and Onasemnogene abeparvovec?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give inactivated vaccines at least 2 weeks before starting corticosteroid prophylaxis where feasible, and follow specialist guidance on scheduling.
What other medicines interact with Hepatitis A vaccine inactivated?
MediHelp also lists interactions of Hepatitis A vaccine inactivated with, for example, Adalimumab, Alefacept, Anakinra. The full list is on the Hepatitis A vaccine inactivated page.
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