Drug interactions
Histrelin + Salbutamol
Severity: Minor
Histrelin and Salbutamol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Androgen deprivation therapy with GnRH agonists such as histrelin may prolong the QT interval, and salbutamol may add a small further effect. Clinical significance is usually modest but relevant in patients with other QT risks.
What this interaction means in plain words
Histrelin and Salbutamol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Histrelin belongs to Musculoskeletal; Salbutamol belongs to Respiratory.
Why it happens
Possible additive QT prolongation; GnRH agonist effect arises from hormonal suppression.
What to do
No routine action is needed; consider ECG and electrolyte checks if the patient has other QT risk factors or uses high-dose salbutamol.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Salbutamol
Other interactions of Histrelin
- Amiodarone + Histrelin Major
- Anagrelide + Histrelin Major
- Histrelin + Thioridazine Major
- Alfuzosin + Histrelin Moderate
- Amisulpride + Histrelin Moderate
- Asenapine + Histrelin Moderate
Frequently asked questions
Can I take Histrelin with Salbutamol?
MediHelp rates the interaction as minor. Histrelin and Salbutamol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Androgen deprivation therapy with GnRH agonists such as histrelin may prolong the QT interval, and salbutamol may add a small further effect. Clinical significance is usually modest but relevant in patients with other QT risks.
How serious is the interaction between Histrelin and Salbutamol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine action is needed; consider ECG and electrolyte checks if the patient has other QT risk factors or uses high-dose salbutamol.
What other medicines interact with Salbutamol?
MediHelp also lists interactions of Salbutamol with, for example, Arsenic trioxide, Carvedilol, Droperidol. The full list is on the Salbutamol page.
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