Drug interactions
Horse chestnut seed + Ketoprofen
Severity: Minor
Horse chestnut seed and Ketoprofen: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Horse chestnut contains aescin and coumarin-like constituents that could theoretically increase bleeding tendency. Combined with an NSAID this may add to bleeding risk, though clinical reports are scarce.
What this interaction means in plain words
Horse chestnut seed and Ketoprofen have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Theoretical additive effects on hemostasis from horse chestnut constituents and NSAID platelet inhibition.
What to do
Monitor for bleeding and bruising; avoid combining before surgery.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Ketoprofen
- Ketoprofen + Ketorolac Contraindicated
- Ketoprofen + Ketorolac intranasal Contraindicated
- Aceclofenac + Ketoprofen Major
- Acemetacin + Ketoprofen Major
- Acetylsalicylic acid + Ketoprofen Major
- Alteplase + Ketoprofen Major
Frequently asked questions
Can I take Horse chestnut seed with Ketoprofen?
MediHelp rates the interaction as minor. Horse chestnut seed and Ketoprofen have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Horse chestnut contains aescin and coumarin-like constituents that could theoretically increase bleeding tendency. Combined with an NSAID this may add to bleeding risk, though clinical reports are scarce.
How serious is the interaction between Horse chestnut seed and Ketoprofen?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for bleeding and bruising; avoid combining before surgery.
What other medicines interact with Ketoprofen?
MediHelp also lists interactions of Ketoprofen with, for example, Ketorolac, Ketorolac intranasal, Aceclofenac. The full list is on the Ketoprofen page.
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