Drug interactions
Hydrochlorothiazide-losartan + Maitake
Severity: Minor
Hydrochlorothiazide-losartan and Maitake: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Maitake mushroom has been reported to lower blood pressure and glucose in limited studies. It may add to the effect of antihypertensives, and theoretically contribute to electrolyte disturbance with hydrochlorothiazide.
What this interaction means in plain words
Hydrochlorothiazide-losartan and Maitake have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible additive blood pressure lowering; the mechanism is not well established.
What to do
Monitor blood pressure if maitake supplements are used regularly, and check electrolytes if symptoms of imbalance occur.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Hydrochlorothiazide-losartan
- Aliskiren + Hydrochlorothiazide-losartan Contraindicated
- Dofetilide + Hydrochlorothiazide-losartan Contraindicated
- Hydrochlorothiazide-losartan + Sparsentan Contraindicated
- Aceclofenac + Hydrochlorothiazide-losartan Major
- Aldesleukin + Hydrochlorothiazide-losartan Major
- Amifostine + Hydrochlorothiazide-losartan Major
Frequently asked questions
Can I take Hydrochlorothiazide-losartan with Maitake?
MediHelp rates the interaction as minor. Hydrochlorothiazide-losartan and Maitake have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Maitake mushroom has been reported to lower blood pressure and glucose in limited studies. It may add to the effect of antihypertensives, and theoretically contribute to electrolyte disturbance with hydrochlorothiazide.
How serious is the interaction between Hydrochlorothiazide-losartan and Maitake?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure if maitake supplements are used regularly, and check electrolytes if symptoms of imbalance occur.
What other medicines interact with Hydrochlorothiazide-losartan?
MediHelp also lists interactions of Hydrochlorothiazide-losartan with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Hydrochlorothiazide-losartan page.
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