Drug interactions
Hydrochlorothiazide-losartan + Mometasone inhaled
Severity: Minor
Hydrochlorothiazide-losartan and Mometasone inhaled: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Systemic corticosteroids can increase potassium loss when used with thiazides. Inhaled mometasone has low systemic absorption, so the effect on potassium is expected to be minimal at usual doses.
What this interaction means in plain words
Hydrochlorothiazide-losartan and Mometasone inhaled have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Corticosteroid mineralocorticoid activity may add to thiazide potassium loss, but systemic exposure from inhalation is low.
What to do
No action is generally needed; check potassium if high doses are used or the patient has other risk factors for hypokalemia.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Hydrochlorothiazide-losartan
- Aliskiren + Hydrochlorothiazide-losartan Contraindicated
- Dofetilide + Hydrochlorothiazide-losartan Contraindicated
- Hydrochlorothiazide-losartan + Sparsentan Contraindicated
- Aceclofenac + Hydrochlorothiazide-losartan Major
- Aldesleukin + Hydrochlorothiazide-losartan Major
- Amifostine + Hydrochlorothiazide-losartan Major
Frequently asked questions
Can I take Hydrochlorothiazide-losartan with Mometasone inhaled?
MediHelp rates the interaction as minor. Hydrochlorothiazide-losartan and Mometasone inhaled have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Systemic corticosteroids can increase potassium loss when used with thiazides. Inhaled mometasone has low systemic absorption, so the effect on potassium is expected to be minimal at usual doses.
How serious is the interaction between Hydrochlorothiazide-losartan and Mometasone inhaled?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No action is generally needed; check potassium if high doses are used or the patient has other risk factors for hypokalemia.
What other medicines interact with Hydrochlorothiazide-losartan?
MediHelp also lists interactions of Hydrochlorothiazide-losartan with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Hydrochlorothiazide-losartan page.
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