Drug interactions
Hydrochlorothiazide-losartan + Shepherd's purse
Severity: Minor
Hydrochlorothiazide-losartan and Shepherd's purse: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Shepherd's purse has been suggested to affect blood pressure and could theoretically interfere with the control achieved by antihypertensive therapy. Reliable clinical data are lacking.
What this interaction means in plain words
Hydrochlorothiazide-losartan and Shepherd's purse have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Mechanism not established; theoretical effect on vascular tone.
What to do
Avoid unnecessary use of the herb and monitor blood pressure if taken.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Hydrochlorothiazide-losartan
- Aliskiren + Hydrochlorothiazide-losartan Contraindicated
- Dofetilide + Hydrochlorothiazide-losartan Contraindicated
- Hydrochlorothiazide-losartan + Sparsentan Contraindicated
- Aceclofenac + Hydrochlorothiazide-losartan Major
- Aldesleukin + Hydrochlorothiazide-losartan Major
- Amifostine + Hydrochlorothiazide-losartan Major
Frequently asked questions
Can I take Hydrochlorothiazide-losartan with Shepherd's purse?
MediHelp rates the interaction as minor. Hydrochlorothiazide-losartan and Shepherd's purse have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Shepherd's purse has been suggested to affect blood pressure and could theoretically interfere with the control achieved by antihypertensive therapy. Reliable clinical data are lacking.
How serious is the interaction between Hydrochlorothiazide-losartan and Shepherd's purse?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid unnecessary use of the herb and monitor blood pressure if taken.
What other medicines interact with Hydrochlorothiazide-losartan?
MediHelp also lists interactions of Hydrochlorothiazide-losartan with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Hydrochlorothiazide-losartan page.
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