Drug interactions
Hydrochlorothiazide-telmisartan + Quinine
Severity: Minor
Hydrochlorothiazide-telmisartan and Quinine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Quinine is partly cleared by the kidney, so competition with thiazides for tubular secretion is theoretically possible. Thiazide-induced hypokalemia or hypomagnesemia could also increase the risk of QT prolongation with quinine.
What this interaction means in plain words
Hydrochlorothiazide-telmisartan and Quinine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Hydrochlorothiazide-telmisartan belongs to Cardiovascular; Quinine belongs to Anti Parasitic.
Why it happens
Theoretical competition for renal tubular cationic secretion; electrolyte disturbance may add to quinine's QT effect.
What to do
Check potassium and magnesium and correct deficits before and during quinine therapy. Consider an ECG in patients with other QT risk factors.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Hydrochlorothiazide-telmisartan
- Aliskiren + Hydrochlorothiazide-telmisartan Contraindicated
- Dofetilide + Hydrochlorothiazide-telmisartan Contraindicated
- Hydrochlorothiazide-telmisartan + Sparsentan Contraindicated
- Aldesleukin + Hydrochlorothiazide-telmisartan Major
- Amifostine + Hydrochlorothiazide-telmisartan Major
- Amiloride + Hydrochlorothiazide-telmisartan Major
Other interactions of Quinine
- Arsenic trioxide + Quinine Contraindicated
- Dofetilide + Quinine Contraindicated
- Dronedarone + Quinine Contraindicated
- Ibutilide + Quinine Contraindicated
- Mefloquine + Quinine Contraindicated
- Nilotinib + Quinine Contraindicated
Frequently asked questions
Can I take Hydrochlorothiazide-telmisartan with Quinine?
MediHelp rates the interaction as minor. Hydrochlorothiazide-telmisartan and Quinine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Quinine is partly cleared by the kidney, so competition with thiazides for tubular secretion is theoretically possible. Thiazide-induced hypokalemia or hypomagnesemia could also increase the risk of QT prolongation with quinine.
How serious is the interaction between Hydrochlorothiazide-telmisartan and Quinine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check potassium and magnesium and correct deficits before and during quinine therapy. Consider an ECG in patients with other QT risk factors.
What other medicines interact with Hydrochlorothiazide-telmisartan?
MediHelp also lists interactions of Hydrochlorothiazide-telmisartan with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Hydrochlorothiazide-telmisartan page.
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