Drug interactions
Ibuprofen + Terazosin
Severity: Minor
Ibuprofen and Terazosin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ibuprofen may attenuate the blood pressure lowering effect of terazosin, especially at higher doses or with prolonged use. The effect is typically modest.
What this interaction means in plain words
Ibuprofen and Terazosin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Ibuprofen belongs to Musculoskeletal; Terazosin belongs to Genitourinary.
Why it happens
NSAID inhibition of prostaglandin synthesis causes sodium and fluid retention, opposing antihypertensive action.
What to do
Monitor blood pressure if ibuprofen is used regularly and keep NSAID doses and duration to a minimum.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Terazosin
- Alfuzosin + Terazosin Major
- Amifostine + Terazosin Major
- Avanafil + Terazosin Major
- Doxazosin + Terazosin Major
- Dutasteride-tamsulosin + Terazosin Major
- Lofexidine + Terazosin Major
Other interactions of Ibuprofen
- Ibuprofen + Ketorolac Contraindicated
- Ibuprofen + Ketorolac intranasal Contraindicated
- Acemetacin + Ibuprofen Major
- Alteplase + Ibuprofen Major
- Amiloride + Ibuprofen Major
- Apixaban + Ibuprofen Major
Frequently asked questions
Can I take Ibuprofen with Terazosin?
MediHelp rates the interaction as minor. Ibuprofen and Terazosin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Ibuprofen may attenuate the blood pressure lowering effect of terazosin, especially at higher doses or with prolonged use. The effect is typically modest.
How serious is the interaction between Ibuprofen and Terazosin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure if ibuprofen is used regularly and keep NSAID doses and duration to a minimum.
What other medicines interact with Terazosin?
MediHelp also lists interactions of Terazosin with, for example, Alfuzosin, Amifostine, Avanafil. The full list is on the Terazosin page.
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