Drug interactions
Indacaterol inhaled + Propafenone
Severity: Moderate
Indacaterol inhaled and Propafenone: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Indacaterol, a long-acting beta-agonist, can prolong QTc and cause hypokalemia and tachycardia, which may add to the arrhythmic risk of propafenone.
What this interaction means in plain words
Indacaterol inhaled and Propafenone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive pharmacodynamic effects on QT interval and cardiac excitability.
What to do
Monitor ECG and serum potassium, particularly in patients with structural heart disease.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Propafenone
- Dofetilide + Propafenone Contraindicated
- Dronedarone + Propafenone Contraindicated
- Nilotinib + Propafenone Contraindicated
- Nirmatrelvir / ritonavir + Propafenone Contraindicated
- Nirmatrelvir + Propafenone Contraindicated
- Pimozide + Propafenone Contraindicated
Frequently asked questions
Can I take Indacaterol inhaled with Propafenone?
MediHelp rates the interaction as moderate. Indacaterol inhaled and Propafenone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Indacaterol, a long-acting beta-agonist, can prolong QTc and cause hypokalemia and tachycardia, which may add to the arrhythmic risk of propafenone.
How serious is the interaction between Indacaterol inhaled and Propafenone?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor ECG and serum potassium, particularly in patients with structural heart disease.
What other medicines interact with Propafenone?
MediHelp also lists interactions of Propafenone with, for example, Dofetilide, Dronedarone, Nilotinib. The full list is on the Propafenone page.
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