Drug interactions
Indacaterol inhaled + Vardenafil
Severity: Minor
Indacaterol inhaled and Vardenafil: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Vardenafil has a small QT-prolonging effect and indacaterol, a beta2 agonist, can affect QT interval and heart rate. Combined use may add to the risk of arrhythmia, mainly in susceptible patients.
What this interaction means in plain words
Indacaterol inhaled and Vardenafil have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Additive effects on cardiac repolarization and beta2-mediated cardiovascular stimulation.
What to do
Usually no change is needed; monitor ECG and potassium in patients with known QT prolongation, heart disease or hypokalemia.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Vardenafil
- Amyl nitrite + Vardenafil Contraindicated
- Glyceryl trinitrate pr + Vardenafil Contraindicated
- Isosorbide dinitrate + Vardenafil Contraindicated
- Isosorbide mononitrate + Vardenafil Contraindicated
- Nicorandil + Vardenafil Contraindicated
- Nitroglycerin po + Vardenafil Contraindicated
Frequently asked questions
Can I take Indacaterol inhaled with Vardenafil?
MediHelp rates the interaction as minor. Indacaterol inhaled and Vardenafil have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Vardenafil has a small QT-prolonging effect and indacaterol, a beta2 agonist, can affect QT interval and heart rate. Combined use may add to the risk of arrhythmia, mainly in susceptible patients.
How serious is the interaction between Indacaterol inhaled and Vardenafil?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Usually no change is needed; monitor ECG and potassium in patients with known QT prolongation, heart disease or hypokalemia.
What other medicines interact with Vardenafil?
MediHelp also lists interactions of Vardenafil with, for example, Amyl nitrite, Glyceryl trinitrate pr, Isosorbide dinitrate. The full list is on the Vardenafil page.
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