Drug interactions
Indapamide + Oliceridine
Severity: Minor
Indapamide and Oliceridine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Opioids can stimulate antidiuretic hormone release and may cause urinary retention, which can blunt diuretic effect. Opioids also add to hypotension and orthostatic effects with diuretics, and oliceridine is used short term in hospital settings.
What this interaction means in plain words
Indapamide and Oliceridine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Indapamide belongs to Cardiovascular; Oliceridine belongs to Musculoskeletal.
Why it happens
Opioid-induced antidiuretic hormone release and additive hypotensive effect opposing or compounding diuretic actions.
What to do
Monitor urine output, fluid status, sodium and blood pressure during oliceridine use. Adjust the diuretic if diuresis is inadequate or hypotension occurs.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Indapamide
Other interactions of Oliceridine
- Isocarboxazid + Oliceridine Contraindicated
- Alprazolam + Oliceridine Major
- Amiodarone + Oliceridine Major
- Amisulpride + Oliceridine Major
- Amitriptyline + Oliceridine Major
- Amobarbital + Oliceridine Major
Frequently asked questions
Can I take Indapamide with Oliceridine?
MediHelp rates the interaction as minor. Indapamide and Oliceridine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Opioids can stimulate antidiuretic hormone release and may cause urinary retention, which can blunt diuretic effect. Opioids also add to hypotension and orthostatic effects with diuretics, and oliceridine is used short term in hospital settings.
How serious is the interaction between Indapamide and Oliceridine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor urine output, fluid status, sodium and blood pressure during oliceridine use. Adjust the diuretic if diuresis is inadequate or hypotension occurs.
What other medicines interact with Indapamide?
MediHelp also lists interactions of Indapamide with, for example, Adagrasib, Amifostine, Amiodarone. The full list is on the Indapamide page.
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