Drug interactions
Indomethacin + Moxisylyte
Severity: Minor
Indomethacin and Moxisylyte: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Moxisylyte is an alpha-blocking vasodilator, and NSAIDs may reduce vasodilator effects mediated by prostaglandins. Evidence for a clinically relevant loss of effect is limited.
What this interaction means in plain words
Indomethacin and Moxisylyte have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
NSAID inhibition of prostaglandin synthesis may blunt vasodilation; the interaction is largely theoretical.
What to do
Monitor therapeutic response to moxisylyte and consider alternatives if the effect appears reduced.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Indomethacin
- Indomethacin + Ketorolac Contraindicated
- Indomethacin + Ketorolac intranasal Contraindicated
- Aceclofenac + Indomethacin Major
- Acemetacin + Indomethacin Major
- Acetylsalicylic acid + Indomethacin Major
- Alteplase + Indomethacin Major
Frequently asked questions
Can I take Indomethacin with Moxisylyte?
MediHelp rates the interaction as minor. Indomethacin and Moxisylyte have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Moxisylyte is an alpha-blocking vasodilator, and NSAIDs may reduce vasodilator effects mediated by prostaglandins. Evidence for a clinically relevant loss of effect is limited.
How serious is the interaction between Indomethacin and Moxisylyte?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor therapeutic response to moxisylyte and consider alternatives if the effect appears reduced.
What other medicines interact with Indomethacin?
MediHelp also lists interactions of Indomethacin with, for example, Ketorolac, Ketorolac intranasal, Aceclofenac. The full list is on the Indomethacin page.
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