Drug interactions
Indomethacin + Panax ginseng
Severity: Minor
Indomethacin and Panax ginseng: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Panax ginseng has shown antiplatelet activity in laboratory studies, and may alter warfarin response. Combined with indomethacin, a theoretical increase in bleeding risk exists.
What this interaction means in plain words
Indomethacin and Panax ginseng have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible additive antiplatelet effect; evidence is mainly from in vitro and limited clinical data.
What to do
Advise patients to report bleeding or bruising and to stop ginseng before surgery.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Indomethacin
- Indomethacin + Ketorolac Contraindicated
- Indomethacin + Ketorolac intranasal Contraindicated
- Aceclofenac + Indomethacin Major
- Acemetacin + Indomethacin Major
- Acetylsalicylic acid + Indomethacin Major
- Alteplase + Indomethacin Major
Frequently asked questions
Can I take Indomethacin with Panax ginseng?
MediHelp rates the interaction as minor. Indomethacin and Panax ginseng have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Panax ginseng has shown antiplatelet activity in laboratory studies, and may alter warfarin response. Combined with indomethacin, a theoretical increase in bleeding risk exists.
How serious is the interaction between Indomethacin and Panax ginseng?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients to report bleeding or bruising and to stop ginseng before surgery.
What other medicines interact with Indomethacin?
MediHelp also lists interactions of Indomethacin with, for example, Ketorolac, Ketorolac intranasal, Aceclofenac. The full list is on the Indomethacin page.
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