Drug interactions
Indomethacin + Rose hips
Severity: Minor
Indomethacin and Rose hips: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Rose hips contain vitamin C, an organic acid, which has been proposed to compete with indomethacin for renal tubular secretion. Any clinical change in indomethacin exposure is likely trivial.
What this interaction means in plain words
Indomethacin and Rose hips have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Theoretical competition for renal tubular anionic secretion.
What to do
No action is needed for usual dietary or supplement amounts. Monitor for NSAID adverse effects if large supplemental doses are used.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Indomethacin
- Indomethacin + Ketorolac Contraindicated
- Indomethacin + Ketorolac intranasal Contraindicated
- Aceclofenac + Indomethacin Major
- Acemetacin + Indomethacin Major
- Acetylsalicylic acid + Indomethacin Major
- Alteplase + Indomethacin Major
Frequently asked questions
Can I take Indomethacin with Rose hips?
MediHelp rates the interaction as minor. Indomethacin and Rose hips have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Rose hips contain vitamin C, an organic acid, which has been proposed to compete with indomethacin for renal tubular secretion. Any clinical change in indomethacin exposure is likely trivial.
How serious is the interaction between Indomethacin and Rose hips?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No action is needed for usual dietary or supplement amounts. Monitor for NSAID adverse effects if large supplemental doses are used.
What other medicines interact with Indomethacin?
MediHelp also lists interactions of Indomethacin with, for example, Ketorolac, Ketorolac intranasal, Aceclofenac. The full list is on the Indomethacin page.
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