Drug interactions
Influenza a vaccine + Vinblastine
Severity: Moderate
Influenza a vaccine and Vinblastine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Vinblastine causes myelosuppression and immune suppression, which may blunt the antibody response to influenza A (H5N1) vaccine. Patients may be left with less protection than expected.
What this interaction means in plain words
Influenza a vaccine and Vinblastine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Cytotoxic immunosuppression reduces the immune response to vaccination.
What to do
Where possible, vaccinate before starting chemotherapy or between cycles when counts recover, and do not rely on the response alone for protection.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Vinblastine
Frequently asked questions
Can I take Influenza a vaccine with Vinblastine?
MediHelp rates the interaction as moderate. Influenza a vaccine and Vinblastine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Vinblastine causes myelosuppression and immune suppression, which may blunt the antibody response to influenza A (H5N1) vaccine. Patients may be left with less protection than expected.
How serious is the interaction between Influenza a vaccine and Vinblastine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Where possible, vaccinate before starting chemotherapy or between cycles when counts recover, and do not rely on the response alone for protection.
What other medicines interact with Vinblastine?
MediHelp also lists interactions of Vinblastine with, for example, Adenovirus types 4 and 7 live, Apalutamide, Atazanavir. The full list is on the Vinblastine page.
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