Drug interactions
Influenza virus vaccine trivalent recombinant + Ustekinumab
Severity: Minor
Influenza virus vaccine trivalent recombinant and Ustekinumab: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ustekinumab may modestly lower the antibody response to recombinant influenza vaccine. There is no infection risk from the vaccine itself.
What this interaction means in plain words
Influenza virus vaccine trivalent recombinant and Ustekinumab have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Pharmacodynamic: IL-12/23 inhibition may modestly reduce immune responses to vaccine antigens.
What to do
Vaccinate on the usual schedule; no adjustment is required.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Ustekinumab
- Bcg vaccine live + Ustekinumab Contraindicated
- Typhoid vaccine live + Ustekinumab Contraindicated
- Adalimumab + Ustekinumab Major
- Adenovirus types 4 and 7 live + Ustekinumab Major
- Alefacept + Ustekinumab Major
- Anakinra + Ustekinumab Major
Frequently asked questions
Can I take Influenza virus vaccine trivalent recombinant with Ustekinumab?
MediHelp rates the interaction as minor. Influenza virus vaccine trivalent recombinant and Ustekinumab have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Ustekinumab may modestly lower the antibody response to recombinant influenza vaccine. There is no infection risk from the vaccine itself.
How serious is the interaction between Influenza virus vaccine trivalent recombinant and Ustekinumab?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Vaccinate on the usual schedule; no adjustment is required.
What other medicines interact with Ustekinumab?
MediHelp also lists interactions of Ustekinumab with, for example, Bcg vaccine live, Typhoid vaccine live, Adalimumab. The full list is on the Ustekinumab page.
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