Drug reference
ustekinumab
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Gastrointestinal Tract (Monoclonal antibody(GIT))
Mechanism of action
Human IgG1κ monoclonal antibody binds to the p40 protein subunit used by IL-12 and IL-23 cytokines; IL-12 and IL-23 are involved in inflammatory and immune responses (eg, natural killer cell activation, CD4+ T-cell differentiation, and activation).
Common side effects
- Nasopharyngitis
- Cellulitis
- Back pain
- Injection site erythema
Contraindications
- Hypersensitivity Active serious infection Concomitant live vaccines
Related conditions
Frequently asked questions
What drug class is ustekinumab?
ustekinumab belongs to: Gastrointestinal Tract.
How does ustekinumab work?
Human IgG1κ monoclonal antibody binds to the p40 protein subunit used by IL-12 and IL-23 cytokines; IL-12 and IL-23 are involved in inflammatory and immune responses (eg, natural killer cell activation, CD4+ T-cell differentiation, and activation).
What are the common side effects of ustekinumab?
Nasopharyngitis, Cellulitis, Back pain, Injection site erythema
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