Drug interactions
Insulin aspart + Procarbazine
Severity: Moderate
Insulin aspart and Procarbazine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Procarbazine has been associated with altered glycemic control and hypoglycemia in some patients, and its use with insulin may potentiate this effect. The mechanism is not well established and the supporting evidence is limited.
What this interaction means in plain words
Insulin aspart and Procarbazine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Insulin aspart belongs to Endocrine; Procarbazine belongs to Oncology.
Why it happens
Mechanism not established; possible additive glucose-lowering effects.
What to do
Monitor blood glucose regularly during procarbazine therapy and adjust the insulin dose as needed.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Insulin aspart
Other interactions of Procarbazine
- Adenovirus types 4 and 7 live + Procarbazine Contraindicated
- Amitriptyline + Procarbazine Contraindicated
- Amoxapine + Procarbazine Contraindicated
- Atomoxetine + Procarbazine Contraindicated
- Bcg vaccine live + Procarbazine Contraindicated
- Brimonidine + Procarbazine Contraindicated
Frequently asked questions
Can I take Insulin aspart with Procarbazine?
MediHelp rates the interaction as moderate. Insulin aspart and Procarbazine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Procarbazine has been associated with altered glycemic control and hypoglycemia in some patients, and its use with insulin may potentiate this effect. The mechanism is not well established and the supporting evidence is limited.
How serious is the interaction between Insulin aspart and Procarbazine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose regularly during procarbazine therapy and adjust the insulin dose as needed.
What other medicines interact with Insulin aspart?
MediHelp also lists interactions of Insulin aspart with, for example, Alogliptin-pioglitazone, Ethanol, Glimepiride-pioglitazone. The full list is on the Insulin aspart page.
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