Drug interactions
Insulin degludec-liraglutide + Moexipril
Severity: Moderate
Insulin degludec-liraglutide and Moexipril: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
ACE inhibitors may increase insulin sensitivity and the risk of hypoglycemia in patients using insulin or other antidiabetic agents. Risk is greatest soon after starting the ACE inhibitor.
What this interaction means in plain words
Insulin degludec-liraglutide and Moexipril can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Insulin degludec-liraglutide belongs to Endocrine; Moexipril belongs to Cardiovascular.
Why it happens
ACE inhibition may improve insulin sensitivity, adding to the glucose-lowering effect.
What to do
Monitor glucose closely in the first weeks after starting moexipril and reduce insulin dose if hypoglycemia occurs.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Insulin degludec-liraglutide
Other interactions of Moexipril
- Aliskiren + Moexipril Contraindicated
- Moexipril + Protein a column Contraindicated
- Moexipril + Sacubitril / valsartan Contraindicated
- Moexipril + Sacubitril-valsartan Contraindicated
- Amifostine + Moexipril Major
- Amiloride + Moexipril Major
Frequently asked questions
Can I take Insulin degludec-liraglutide with Moexipril?
MediHelp rates the interaction as moderate. Insulin degludec-liraglutide and Moexipril can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. ACE inhibitors may increase insulin sensitivity and the risk of hypoglycemia in patients using insulin or other antidiabetic agents. Risk is greatest soon after starting the ACE inhibitor.
How serious is the interaction between Insulin degludec-liraglutide and Moexipril?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor glucose closely in the first weeks after starting moexipril and reduce insulin dose if hypoglycemia occurs.
What other medicines interact with Insulin degludec-liraglutide?
MediHelp also lists interactions of Insulin degludec-liraglutide with, for example, Albiglutide, Chlorpropamide, Clozapine. The full list is on the Insulin degludec-liraglutide page.
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