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Drug interactions

Insulin degludec-liraglutide + Valsartan

Severity: Minor

Insulin degludec-liraglutide and Valsartan: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Angiotensin receptor blockers may improve insulin sensitivity and slightly enhance the glucose-lowering effect of insulin and other antidiabetic drugs. Hypoglycemia is uncommon but possible after starting the ARB.

What this interaction means in plain words

Insulin degludec-liraglutide and Valsartan have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Insulin degludec-liraglutide belongs to Endocrine; Valsartan belongs to Cardiovascular.

Evidence level: Low

Why it happens

Improved insulin sensitivity from angiotensin II receptor blockade, adding to antidiabetic effects.

What to do

Monitor blood glucose after starting valsartan. Reduce the insulin dose if hypoglycemia occurs.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Insulin degludec-liraglutide with Valsartan?

MediHelp rates the interaction as minor. Insulin degludec-liraglutide and Valsartan have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Angiotensin receptor blockers may improve insulin sensitivity and slightly enhance the glucose-lowering effect of insulin and other antidiabetic drugs. Hypoglycemia is uncommon but possible after starting the ARB.

How serious is the interaction between Insulin degludec-liraglutide and Valsartan?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose after starting valsartan. Reduce the insulin dose if hypoglycemia occurs.

What other medicines interact with Insulin degludec-liraglutide?

MediHelp also lists interactions of Insulin degludec-liraglutide with, for example, Albiglutide, Chlorpropamide, Clozapine. The full list is on the Insulin degludec-liraglutide page.

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