Drug interactions
Ipratropium-salbutamol + Ketorolac
Severity: Minor
Ipratropium-salbutamol and Ketorolac: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
No clinically important interaction is established between inhaled salbutamol-ipratropium and ketorolac. Ketorolac can raise potassium, especially with renal impairment, while salbutamol tends to lower it, so effects are small and opposing. Clinical significance is minimal at usual doses.
What this interaction means in plain words
Ipratropium-salbutamol and Ketorolac have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Ipratropium-salbutamol belongs to Respiratory; Ketorolac belongs to Musculoskeletal.
Why it happens
Opposing minor effects on serum potassium; no established mechanism of clinical significance.
What to do
No routine action is needed; check potassium and renal function if high-dose salbutamol is used in patients with kidney disease or on prolonged ketorolac.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Ipratropium-salbutamol
Other interactions of Ketorolac
- Aceclofenac + Ketorolac Contraindicated
- Acemetacin + Ketorolac Contraindicated
- Acetylsalicylic acid + Ketorolac Contraindicated
- Apixaban + Ketorolac Contraindicated
- Argatroban + Ketorolac Contraindicated
- Aspirin / citric acid / sodium bicarbonate + Ketorolac Contraindicated
Frequently asked questions
Can I take Ipratropium-salbutamol with Ketorolac?
MediHelp rates the interaction as minor. Ipratropium-salbutamol and Ketorolac have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. No clinically important interaction is established between inhaled salbutamol-ipratropium and ketorolac. Ketorolac can raise potassium, especially with renal impairment, while salbutamol tends to lower it, so effects are small and opposing. Clinical significance is minimal at usual doses.
How serious is the interaction between Ipratropium-salbutamol and Ketorolac?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine action is needed; check potassium and renal function if high-dose salbutamol is used in patients with kidney disease or on prolonged ketorolac.
What other medicines interact with Ipratropium-salbutamol?
MediHelp also lists interactions of Ipratropium-salbutamol with, for example, Amisulpride, Arsenic trioxide, Carvedilol. The full list is on the Ipratropium-salbutamol page.
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