Drug interactions
Ipratropium-salbutamol + Lithium
Severity: Minor
Ipratropium-salbutamol and Lithium: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Lithium has been associated with QT prolongation and arrhythmias, particularly at higher concentrations, and salbutamol may add to risk through hypokalemia and tachycardia. At usual inhaled doses the combined effect is generally small.
What this interaction means in plain words
Ipratropium-salbutamol and Lithium have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Ipratropium-salbutamol belongs to Respiratory; Lithium belongs to Central Nervous System.
Why it happens
Possible additive effect on cardiac repolarization and electrolyte shifts.
What to do
No routine change is needed; monitor ECG and electrolytes if lithium levels are high or heart disease is present.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Ipratropium-salbutamol
Other interactions of Lithium
- Lithium + Thioridazine Contraindicated
- Lithium + Vandetanib Contraindicated
- Aceclofenac + Lithium Major
- Acemetacin + Lithium Major
- Amisulpride + Lithium Major
- Amlodipine-benazepril + Lithium Major
Frequently asked questions
Can I take Ipratropium-salbutamol with Lithium?
MediHelp rates the interaction as minor. Ipratropium-salbutamol and Lithium have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Lithium has been associated with QT prolongation and arrhythmias, particularly at higher concentrations, and salbutamol may add to risk through hypokalemia and tachycardia. At usual inhaled doses the combined effect is generally small.
How serious is the interaction between Ipratropium-salbutamol and Lithium?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine change is needed; monitor ECG and electrolytes if lithium levels are high or heart disease is present.
What other medicines interact with Ipratropium-salbutamol?
MediHelp also lists interactions of Ipratropium-salbutamol with, for example, Amisulpride, Arsenic trioxide, Carvedilol. The full list is on the Ipratropium-salbutamol page.
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