Drug interactions
Ipratropium-salbutamol + Phendimetrazine
Severity: Moderate
Ipratropium-salbutamol and Phendimetrazine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Phendimetrazine is a sympathomimetic anorectic and salbutamol is a beta-2 agonist. Together they may add to tachycardia, palpitations, tremor, nervousness and blood pressure elevation.
What this interaction means in plain words
Ipratropium-salbutamol and Phendimetrazine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive sympathomimetic stimulation of the cardiovascular and central nervous systems.
What to do
Monitor heart rate and blood pressure and ask about palpitations and tremor. Consider alternatives to phendimetrazine in patients with cardiovascular disease.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Ipratropium-salbutamol
Frequently asked questions
Can I take Ipratropium-salbutamol with Phendimetrazine?
MediHelp rates the interaction as moderate. Ipratropium-salbutamol and Phendimetrazine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Phendimetrazine is a sympathomimetic anorectic and salbutamol is a beta-2 agonist. Together they may add to tachycardia, palpitations, tremor, nervousness and blood pressure elevation.
How serious is the interaction between Ipratropium-salbutamol and Phendimetrazine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor heart rate and blood pressure and ask about palpitations and tremor. Consider alternatives to phendimetrazine in patients with cardiovascular disease.
What other medicines interact with Ipratropium-salbutamol?
MediHelp also lists interactions of Ipratropium-salbutamol with, for example, Amisulpride, Arsenic trioxide, Carvedilol. The full list is on the Ipratropium-salbutamol page.
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