Drug interactions
Isoproterenol + Olodaterol inhaled
Severity: Moderate
Isoproterenol and Olodaterol inhaled: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Olodaterol is a long-acting beta-2 agonist, and adding isoproterenol produces additive beta-adrenergic effects. This may cause tachycardia, palpitations, tremor, arrhythmias and hypokalemia.
What this interaction means in plain words
Isoproterenol and Olodaterol inhaled can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive beta-adrenergic receptor agonism.
What to do
Avoid concurrent use unless clearly necessary. If combined, monitor heart rate, ECG and serum potassium.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Isoproterenol
Frequently asked questions
Can I take Isoproterenol with Olodaterol inhaled?
MediHelp rates the interaction as moderate. Isoproterenol and Olodaterol inhaled can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Olodaterol is a long-acting beta-2 agonist, and adding isoproterenol produces additive beta-adrenergic effects. This may cause tachycardia, palpitations, tremor, arrhythmias and hypokalemia.
How serious is the interaction between Isoproterenol and Olodaterol inhaled?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid concurrent use unless clearly necessary. If combined, monitor heart rate, ECG and serum potassium.
What other medicines interact with Isoproterenol?
MediHelp also lists interactions of Isoproterenol with, for example, Adrenaline-articaine, Bisoprolol, Budesonide-formoterol. The full list is on the Isoproterenol page.
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