Drug interactions
Isoproterenol + Phendimetrazine
Severity: Moderate
Isoproterenol and Phendimetrazine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Phendimetrazine is a sympathomimetic anorectic that raises heart rate and blood pressure. Combined with isoproterenol it may add to tachycardia, palpitations and arrhythmia risk.
What this interaction means in plain words
Isoproterenol and Phendimetrazine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive sympathomimetic effects from indirect catecholamine release and direct beta-agonism.
What to do
Monitor heart rate, blood pressure and ECG during co-use. Consider holding phendimetrazine in patients needing isoproterenol.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Isoproterenol
Frequently asked questions
Can I take Isoproterenol with Phendimetrazine?
MediHelp rates the interaction as moderate. Isoproterenol and Phendimetrazine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Phendimetrazine is a sympathomimetic anorectic that raises heart rate and blood pressure. Combined with isoproterenol it may add to tachycardia, palpitations and arrhythmia risk.
How serious is the interaction between Isoproterenol and Phendimetrazine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor heart rate, blood pressure and ECG during co-use. Consider holding phendimetrazine in patients needing isoproterenol.
What other medicines interact with Isoproterenol?
MediHelp also lists interactions of Isoproterenol with, for example, Adrenaline-articaine, Bisoprolol, Budesonide-formoterol. The full list is on the Isoproterenol page.
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