Drug interactions
Isradipine + Umeclidinium-vilanterol
Severity: Minor
Isradipine and Umeclidinium-vilanterol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Isradipine is a dihydropyridine calcium channel blocker that does not meaningfully prolong the QT interval. The legacy concern is not well supported, and any effect is limited to modest changes in heart rate and blood pressure from opposing vascular effects.
What this interaction means in plain words
Isradipine and Umeclidinium-vilanterol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
No established QT interaction; possible minor opposing hemodynamic effects, with isradipine metabolized by CYP3A4 not affected by vilanterol.
What to do
No specific action is required beyond routine monitoring of blood pressure and heart rate.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Umeclidinium-vilanterol
Frequently asked questions
Can I take Isradipine with Umeclidinium-vilanterol?
MediHelp rates the interaction as minor. Isradipine and Umeclidinium-vilanterol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Isradipine is a dihydropyridine calcium channel blocker that does not meaningfully prolong the QT interval. The legacy concern is not well supported, and any effect is limited to modest changes in heart rate and blood pressure from opposing vascular effects.
How serious is the interaction between Isradipine and Umeclidinium-vilanterol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No specific action is required beyond routine monitoring of blood pressure and heart rate.
What other medicines interact with Umeclidinium-vilanterol?
MediHelp also lists interactions of Umeclidinium-vilanterol with, for example, Aclidinium, Amiodarone, Amitriptyline. The full list is on the Umeclidinium-vilanterol page.
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