Drug interactions
Japanese encephalitis virus vaccine + Ustekinumab
Severity: Minor
Japanese encephalitis virus vaccine and Ustekinumab: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
The commonly used Japanese encephalitis vaccine is inactivated, so it is safe, but the immune response in patients on ustekinumab may be lower.
What this interaction means in plain words
Japanese encephalitis virus vaccine and Ustekinumab have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Pharmacodynamic: IL-12/23 inhibition may modestly reduce vaccine responses.
What to do
Vaccinate well before travel, and confirm the product is non-live; consider checking antibody titres if protection is critical.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Ustekinumab
- Bcg vaccine live + Ustekinumab Contraindicated
- Typhoid vaccine live + Ustekinumab Contraindicated
- Adalimumab + Ustekinumab Major
- Adenovirus types 4 and 7 live + Ustekinumab Major
- Alefacept + Ustekinumab Major
- Anakinra + Ustekinumab Major
Frequently asked questions
Can I take Japanese encephalitis virus vaccine with Ustekinumab?
MediHelp rates the interaction as minor. Japanese encephalitis virus vaccine and Ustekinumab have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. The commonly used Japanese encephalitis vaccine is inactivated, so it is safe, but the immune response in patients on ustekinumab may be lower.
How serious is the interaction between Japanese encephalitis virus vaccine and Ustekinumab?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Vaccinate well before travel, and confirm the product is non-live; consider checking antibody titres if protection is critical.
What other medicines interact with Ustekinumab?
MediHelp also lists interactions of Ustekinumab with, for example, Bcg vaccine live, Typhoid vaccine live, Adalimumab. The full list is on the Ustekinumab page.
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