Drug interactions
Juniper + Tolazamide
Severity: Minor
Juniper and Tolazamide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Juniper preparations have shown glucose-lowering activity in animal studies, so taking them with a sulfonylurea could in theory add to the risk of hypoglycemia. Human evidence is lacking, and the clinical relevance is uncertain.
What this interaction means in plain words
Juniper and Tolazamide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible additive blood glucose lowering; the mechanism of juniper's effect is not well established.
What to do
Advise patients to tell the prescriber about juniper use and to monitor blood glucose more often when starting or stopping it. Adjust tolazamide only if hypoglycemia occurs.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Juniper and Tolazamide, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 14 days on the web. No card needed.
Other interactions of Tolazamide
- Disopyramide + Tolazamide Major
- Insulin degludec-liraglutide + Tolazamide Major
- Aceclofenac + Tolazamide Moderate
- Acemetacin + Tolazamide Moderate
- Acetylsalicylic acid + Tolazamide Moderate
- Albiglutide + Tolazamide Moderate
Frequently asked questions
Can I take Juniper with Tolazamide?
MediHelp rates the interaction as minor. Juniper and Tolazamide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Juniper preparations have shown glucose-lowering activity in animal studies, so taking them with a sulfonylurea could in theory add to the risk of hypoglycemia. Human evidence is lacking, and the clinical relevance is uncertain.
How serious is the interaction between Juniper and Tolazamide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients to tell the prescriber about juniper use and to monitor blood glucose more often when starting or stopping it. Adjust tolazamide only if hypoglycemia occurs.
What other medicines interact with Tolazamide?
MediHelp also lists interactions of Tolazamide with, for example, Disopyramide, Insulin degludec-liraglutide, Aceclofenac. The full list is on the Tolazamide page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
