Drug interactions
Juniper + Tolbutamide
Severity: Minor
Juniper and Tolbutamide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Juniper berry preparations have shown glucose-lowering effects in animal studies. Combined with tolbutamide this could theoretically add to hypoglycemia, but no human data confirm it.
What this interaction means in plain words
Juniper and Tolbutamide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible additive blood glucose lowering based on preclinical data.
What to do
Monitor blood glucose if juniper products are taken regularly with tolbutamide.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Tolbutamide
- Glyburide-metformin + Tolbutamide Major
- Insulin degludec-liraglutide + Tolbutamide Major
- Aceclofenac + Tolbutamide Moderate
- Acemetacin + Tolbutamide Moderate
- Acetylsalicylic acid + Tolbutamide Moderate
- Albiglutide + Tolbutamide Moderate
Frequently asked questions
Can I take Juniper with Tolbutamide?
MediHelp rates the interaction as minor. Juniper and Tolbutamide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Juniper berry preparations have shown glucose-lowering effects in animal studies. Combined with tolbutamide this could theoretically add to hypoglycemia, but no human data confirm it.
How serious is the interaction between Juniper and Tolbutamide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose if juniper products are taken regularly with tolbutamide.
What other medicines interact with Tolbutamide?
MediHelp also lists interactions of Tolbutamide with, for example, Glyburide-metformin, Insulin degludec-liraglutide, Aceclofenac. The full list is on the Tolbutamide page.
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