Drug interactions
Ketoprofen + Methyl aminolevulinate
Severity: Moderate
Ketoprofen and Methyl aminolevulinate: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ketoprofen is a known photosensitizer, and methyl aminolevulinate is used topically with light in photodynamic therapy, so the skin reaction at the treated site could be intensified. Systemic exposure to the topical agent is minimal.
What this interaction means in plain words
Ketoprofen and Methyl aminolevulinate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Possible additive phototoxicity at the illuminated skin site.
What to do
Avoid topical ketoprofen on or near the treatment area and counsel light protection after therapy. Consider holding systemic ketoprofen around treatment if practical.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Ketoprofen
- Ketoprofen + Ketorolac Contraindicated
- Ketoprofen + Ketorolac intranasal Contraindicated
- Aceclofenac + Ketoprofen Major
- Acemetacin + Ketoprofen Major
- Acetylsalicylic acid + Ketoprofen Major
- Alteplase + Ketoprofen Major
Frequently asked questions
Can I take Ketoprofen with Methyl aminolevulinate?
MediHelp rates the interaction as moderate. Ketoprofen and Methyl aminolevulinate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Ketoprofen is a known photosensitizer, and methyl aminolevulinate is used topically with light in photodynamic therapy, so the skin reaction at the treated site could be intensified. Systemic exposure to the topical agent is minimal.
How serious is the interaction between Ketoprofen and Methyl aminolevulinate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid topical ketoprofen on or near the treatment area and counsel light protection after therapy. Consider holding systemic ketoprofen around treatment if practical.
What other medicines interact with Ketoprofen?
MediHelp also lists interactions of Ketoprofen with, for example, Ketorolac, Ketorolac intranasal, Aceclofenac. The full list is on the Ketoprofen page.
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