Drug interactions
Ketoprofen + Noni juice
Severity: Moderate
Ketoprofen and Noni juice: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Noni juice has a high potassium content, and NSAIDs can impair renal potassium excretion by suppressing renin and aldosterone. Hyperkalemia is possible with large intake, particularly in kidney disease or with other potassium-raising drugs.
What this interaction means in plain words
Ketoprofen and Noni juice can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive potassium load from noni juice with NSAID-induced reduction of renal potassium excretion.
What to do
Avoid regular noni juice in patients with renal impairment or on ACE inhibitors, ARBs or potassium-sparing diuretics; check serum potassium if used.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Ketoprofen
- Ketoprofen + Ketorolac Contraindicated
- Ketoprofen + Ketorolac intranasal Contraindicated
- Aceclofenac + Ketoprofen Major
- Acemetacin + Ketoprofen Major
- Acetylsalicylic acid + Ketoprofen Major
- Alteplase + Ketoprofen Major
Frequently asked questions
Can I take Ketoprofen with Noni juice?
MediHelp rates the interaction as moderate. Ketoprofen and Noni juice can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Noni juice has a high potassium content, and NSAIDs can impair renal potassium excretion by suppressing renin and aldosterone. Hyperkalemia is possible with large intake, particularly in kidney disease or with other potassium-raising drugs.
How serious is the interaction between Ketoprofen and Noni juice?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid regular noni juice in patients with renal impairment or on ACE inhibitors, ARBs or potassium-sparing diuretics; check serum potassium if used.
What other medicines interact with Ketoprofen?
MediHelp also lists interactions of Ketoprofen with, for example, Ketorolac, Ketorolac intranasal, Aceclofenac. The full list is on the Ketoprofen page.
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