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Drug interactions

Ketoprofen + Pau d'arco

Severity: Minor

Ketoprofen and Pau d'arco: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Pau d'arco is reported to have antiplatelet or anticoagulant-like properties, and ketoprofen inhibits platelet function and can irritate the gastric mucosa. Together they may raise the risk of bleeding, though the data are limited.

What this interaction means in plain words

Ketoprofen and Pau d'arco have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Evidence level: Low

Why it happens

Possible additive impairment of hemostasis; the herb's effect is theoretical and not well characterised.

What to do

Ask patients about herbal use and advise against pau d'arco during regular NSAID therapy. Monitor for bruising, melena or other bleeding if they are used together.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Ketoprofen with Pau d'arco?

MediHelp rates the interaction as minor. Ketoprofen and Pau d'arco have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Pau d'arco is reported to have antiplatelet or anticoagulant-like properties, and ketoprofen inhibits platelet function and can irritate the gastric mucosa. Together they may raise the risk of bleeding, though the data are limited.

How serious is the interaction between Ketoprofen and Pau d'arco?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Ask patients about herbal use and advise against pau d'arco during regular NSAID therapy. Monitor for bruising, melena or other bleeding if they are used together.

What other medicines interact with Ketoprofen?

MediHelp also lists interactions of Ketoprofen with, for example, Ketorolac, Ketorolac intranasal, Aceclofenac. The full list is on the Ketoprofen page.

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