Drug interactions
Ketoprofen + Reishi
Severity: Minor
Ketoprofen and Reishi: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Reishi mushroom has been reported to inhibit platelet aggregation. Combined with ketoprofen, bleeding risk may be modestly increased, though evidence is limited.
What this interaction means in plain words
Ketoprofen and Reishi have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible additive antiplatelet effect; the herbal mechanism is not well established.
What to do
Advise patients to report reishi use and monitor for bruising or bleeding. Consider avoiding the herb in patients at high bleeding risk.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Ketoprofen
- Ketoprofen + Ketorolac Contraindicated
- Ketoprofen + Ketorolac intranasal Contraindicated
- Aceclofenac + Ketoprofen Major
- Acemetacin + Ketoprofen Major
- Acetylsalicylic acid + Ketoprofen Major
- Alteplase + Ketoprofen Major
Frequently asked questions
Can I take Ketoprofen with Reishi?
MediHelp rates the interaction as minor. Ketoprofen and Reishi have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Reishi mushroom has been reported to inhibit platelet aggregation. Combined with ketoprofen, bleeding risk may be modestly increased, though evidence is limited.
How serious is the interaction between Ketoprofen and Reishi?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients to report reishi use and monitor for bruising or bleeding. Consider avoiding the herb in patients at high bleeding risk.
What other medicines interact with Ketoprofen?
MediHelp also lists interactions of Ketoprofen with, for example, Ketorolac, Ketorolac intranasal, Aceclofenac. The full list is on the Ketoprofen page.
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