Drug interactions
Ketoprofen + Saw palmetto
Severity: Minor
Ketoprofen and Saw palmetto: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Saw palmetto has been associated with isolated reports of bleeding and may theoretically add to the bleeding tendency of NSAIDs. The evidence is weak.
What this interaction means in plain words
Ketoprofen and Saw palmetto have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Ketoprofen belongs to Musculoskeletal; Saw palmetto belongs to Gastrointestinal Tract.
Why it happens
Possible weak antiplatelet or cyclooxygenase-inhibiting activity of saw palmetto; mechanism not firmly established.
What to do
Ask patients about herbal use and advise reporting unusual bruising or bleeding; stop the supplement if bleeding occurs.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Ketoprofen
- Ketoprofen + Ketorolac Contraindicated
- Ketoprofen + Ketorolac intranasal Contraindicated
- Aceclofenac + Ketoprofen Major
- Acemetacin + Ketoprofen Major
- Acetylsalicylic acid + Ketoprofen Major
- Alteplase + Ketoprofen Major
Other interactions of Saw palmetto
- Aspirin rectal + Saw palmetto Moderate
- Aspirin + Saw palmetto Moderate
- Dabigatran + Saw palmetto Moderate
- Desirudin + Saw palmetto Moderate
- Ketorolac + Saw palmetto Moderate
- Meclofenamate + Saw palmetto Moderate
Frequently asked questions
Can I take Ketoprofen with Saw palmetto?
MediHelp rates the interaction as minor. Ketoprofen and Saw palmetto have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Saw palmetto has been associated with isolated reports of bleeding and may theoretically add to the bleeding tendency of NSAIDs. The evidence is weak.
How serious is the interaction between Ketoprofen and Saw palmetto?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Ask patients about herbal use and advise reporting unusual bruising or bleeding; stop the supplement if bleeding occurs.
What other medicines interact with Ketoprofen?
MediHelp also lists interactions of Ketoprofen with, for example, Ketorolac, Ketorolac intranasal, Aceclofenac. The full list is on the Ketoprofen page.
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