Drug interactions
Levetiracetam + Olanzapine
Severity: Minor
Levetiracetam and Olanzapine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs can cause somnolence and dizziness, so combined use may increase drowsiness and impair psychomotor performance. Levetiracetam may also cause behavioral changes that could complicate psychiatric treatment.
What this interaction means in plain words
Levetiracetam and Olanzapine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Levetiracetam belongs to Central Nervous System; Olanzapine belongs to Central Nervous System.
Why it happens
Additive central nervous system depressant effects.
What to do
Warn patients about drowsiness and driving or operating machinery. Monitor for excessive sedation and mood or behavioral changes.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Levetiracetam and Olanzapine, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 14 days on the web. No card needed.
Other interactions of Olanzapine
Other interactions of Levetiracetam
Frequently asked questions
Can I take Levetiracetam with Olanzapine?
MediHelp rates the interaction as minor. Levetiracetam and Olanzapine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Both drugs can cause somnolence and dizziness, so combined use may increase drowsiness and impair psychomotor performance. Levetiracetam may also cause behavioral changes that could complicate psychiatric treatment.
How serious is the interaction between Levetiracetam and Olanzapine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Warn patients about drowsiness and driving or operating machinery. Monitor for excessive sedation and mood or behavioral changes.
What other medicines interact with Olanzapine?
MediHelp also lists interactions of Olanzapine with, for example, Amisulpride, Amoxapine, Apomorphine. The full list is on the Olanzapine page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
