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Drug interactions

Levetiracetam + Olopatadine intranasal

Severity: Minor

Levetiracetam and Olopatadine intranasal: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Intranasal olopatadine is an antihistamine that can cause somnolence in some users. Combined with levetiracetam, drowsiness may be somewhat increased.

What this interaction means in plain words

Levetiracetam and Olopatadine intranasal have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Evidence level: Low

Why it happens

Additive mild central nervous system depression (pharmacodynamic).

What to do

Advise patients to note any increased drowsiness before driving. Dosing changes are not usually needed.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Levetiracetam with Olopatadine intranasal?

MediHelp rates the interaction as minor. Levetiracetam and Olopatadine intranasal have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Intranasal olopatadine is an antihistamine that can cause somnolence in some users. Combined with levetiracetam, drowsiness may be somewhat increased.

How serious is the interaction between Levetiracetam and Olopatadine intranasal?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients to note any increased drowsiness before driving. Dosing changes are not usually needed.

What other medicines interact with Levetiracetam?

MediHelp also lists interactions of Levetiracetam with, for example, Oliceridine, Opium tincture, Sodium oxybate. The full list is on the Levetiracetam page.

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