Drug interactions
Levetiracetam + Thiothixene
Severity: Moderate
Levetiracetam and Thiothixene: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs can cause drowsiness and impaired psychomotor performance. Used together, sedation and dizziness may be more pronounced, increasing the risk of falls and impaired driving.
What this interaction means in plain words
Levetiracetam and Thiothixene can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive central nervous system depressant effects.
What to do
Monitor for excessive sedation, particularly after starting or increasing either drug, and counsel patients about driving and operating machinery. Reduce the dose if sedation becomes troublesome.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Levetiracetam
Frequently asked questions
Can I take Levetiracetam with Thiothixene?
MediHelp rates the interaction as moderate. Levetiracetam and Thiothixene can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs can cause drowsiness and impaired psychomotor performance. Used together, sedation and dizziness may be more pronounced, increasing the risk of falls and impaired driving.
How serious is the interaction between Levetiracetam and Thiothixene?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for excessive sedation, particularly after starting or increasing either drug, and counsel patients about driving and operating machinery. Reduce the dose if sedation becomes troublesome.
What other medicines interact with Levetiracetam?
MediHelp also lists interactions of Levetiracetam with, for example, Oliceridine, Opium tincture, Sodium oxybate. The full list is on the Levetiracetam page.
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