Drug interactions
Levobetaxolol + Nebivolol
Severity: Moderate
Levobetaxolol and Nebivolol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Levobetaxolol is a beta blocker, and although it is used in ophthalmic form, it can be absorbed systemically. Combined with oral nebivolol it may add to bradycardia, hypotension and reduced cardiac contractility.
What this interaction means in plain words
Levobetaxolol and Nebivolol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive beta-adrenergic blockade.
What to do
Monitor heart rate and blood pressure when starting or adjusting the ophthalmic beta blocker, and consider a non-beta-blocker glaucoma agent if bradycardia occurs.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Nebivolol
- Acebutolol + Nebivolol Major
- Aldesleukin + Nebivolol Major
- Amiodarone + Nebivolol Major
- Atenolol-chlorthalidone + Nebivolol Major
- Atenolol + Nebivolol Major
- Betaxolol + Nebivolol Major
Frequently asked questions
Can I take Levobetaxolol with Nebivolol?
MediHelp rates the interaction as moderate. Levobetaxolol and Nebivolol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Levobetaxolol is a beta blocker, and although it is used in ophthalmic form, it can be absorbed systemically. Combined with oral nebivolol it may add to bradycardia, hypotension and reduced cardiac contractility.
How serious is the interaction between Levobetaxolol and Nebivolol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor heart rate and blood pressure when starting or adjusting the ophthalmic beta blocker, and consider a non-beta-blocker glaucoma agent if bradycardia occurs.
What other medicines interact with Nebivolol?
MediHelp also lists interactions of Nebivolol with, for example, Acebutolol, Aldesleukin, Amiodarone. The full list is on the Nebivolol page.
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