Drug interactions
Levofloxacin + Methyl aminolevulinate
Severity: Moderate
Levofloxacin and Methyl aminolevulinate: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both agents can cause photosensitivity, so combining them may increase the risk of exaggerated skin reactions after light exposure. Methyl aminolevulinate is applied topically with lamp illumination during photodynamic therapy.
What this interaction means in plain words
Levofloxacin and Methyl aminolevulinate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive phototoxicity from two photosensitizing agents.
What to do
Consider deferring photodynamic therapy until the fluoroquinolone course is finished. Otherwise counsel the patient on strict sun protection and watch for severe skin reactions.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Levofloxacin
- Dronedarone + Levofloxacin Contraindicated
- Ibutilide + Levofloxacin Contraindicated
- Levofloxacin + Thioridazine Contraindicated
- Levofloxacin + Vandetanib Contraindicated
- Levofloxacin + Ziprasidone Contraindicated
- Adagrasib + Levofloxacin Major
Frequently asked questions
Can I take Levofloxacin with Methyl aminolevulinate?
MediHelp rates the interaction as moderate. Levofloxacin and Methyl aminolevulinate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both agents can cause photosensitivity, so combining them may increase the risk of exaggerated skin reactions after light exposure. Methyl aminolevulinate is applied topically with lamp illumination during photodynamic therapy.
How serious is the interaction between Levofloxacin and Methyl aminolevulinate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Consider deferring photodynamic therapy until the fluoroquinolone course is finished. Otherwise counsel the patient on strict sun protection and watch for severe skin reactions.
What other medicines interact with Levofloxacin?
MediHelp also lists interactions of Levofloxacin with, for example, Dronedarone, Ibutilide, Thioridazine. The full list is on the Levofloxacin page.
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