Drug interactions
Levosalbutamol + Procarbazine
Severity: Moderate
Levosalbutamol and Procarbazine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Procarbazine has weak monoamine oxidase inhibitory activity, which may potentiate sympathomimetic amines. Levosalbutamol is a beta-2 agonist with little reliance on MAO metabolism, but cardiovascular effects such as tachycardia or blood pressure rises may be enhanced.
What this interaction means in plain words
Levosalbutamol and Procarbazine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Levosalbutamol belongs to Respiratory; Procarbazine belongs to Oncology.
Why it happens
Possible potentiation of adrenergic effects through MAO inhibition by procarbazine.
What to do
Monitor heart rate and blood pressure when levosalbutamol is used in a patient on procarbazine. Report palpitations or headache promptly and reduce the bronchodilator dose if they occur.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Levosalbutamol
Other interactions of Procarbazine
- Adenovirus types 4 and 7 live + Procarbazine Contraindicated
- Amitriptyline + Procarbazine Contraindicated
- Amoxapine + Procarbazine Contraindicated
- Atomoxetine + Procarbazine Contraindicated
- Bcg vaccine live + Procarbazine Contraindicated
- Brimonidine + Procarbazine Contraindicated
Frequently asked questions
Can I take Levosalbutamol with Procarbazine?
MediHelp rates the interaction as moderate. Levosalbutamol and Procarbazine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Procarbazine has weak monoamine oxidase inhibitory activity, which may potentiate sympathomimetic amines. Levosalbutamol is a beta-2 agonist with little reliance on MAO metabolism, but cardiovascular effects such as tachycardia or blood pressure rises may be enhanced.
How serious is the interaction between Levosalbutamol and Procarbazine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor heart rate and blood pressure when levosalbutamol is used in a patient on procarbazine. Report palpitations or headache promptly and reduce the bronchodilator dose if they occur.
What other medicines interact with Levosalbutamol?
MediHelp also lists interactions of Levosalbutamol with, for example, Amisulpride, Carvedilol, Fexinidazole. The full list is on the Levosalbutamol page.
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