Drug interactions
Linagliptin-metformin + Maitake
Severity: Minor
Linagliptin-metformin and Maitake: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Maitake mushroom extracts lowered blood glucose in animal studies, so an additive effect with metformin and linagliptin is possible. Human data are lacking and the risk of hypoglycemia with these agents alone is low.
What this interaction means in plain words
Linagliptin-metformin and Maitake have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Theoretical additive glucose-lowering effect, possibly through improved insulin sensitivity.
What to do
Monitor glucose when maitake supplements are started or stopped and adjust therapy if needed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Linagliptin-metformin
Frequently asked questions
Can I take Linagliptin-metformin with Maitake?
MediHelp rates the interaction as minor. Linagliptin-metformin and Maitake have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Maitake mushroom extracts lowered blood glucose in animal studies, so an additive effect with metformin and linagliptin is possible. Human data are lacking and the risk of hypoglycemia with these agents alone is low.
How serious is the interaction between Linagliptin-metformin and Maitake?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor glucose when maitake supplements are started or stopped and adjust therapy if needed.
What other medicines interact with Linagliptin-metformin?
MediHelp also lists interactions of Linagliptin-metformin with, for example, Apalutamide, Carbamazepine, Contrast media. The full list is on the Linagliptin-metformin page.
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