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Drug interactions

Linagliptin-metformin + Norgestimate

Severity: Minor

Linagliptin-metformin and Norgestimate: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Norgestimate-containing contraceptives can have a small effect on glucose tolerance. Significant loss of glycemic control is unlikely with modern low-dose products.

What this interaction means in plain words

Linagliptin-metformin and Norgestimate have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Evidence level: Low

Why it happens

Hormonal effects cause mild insulin resistance, opposing antidiabetic action.

What to do

Monitor blood glucose after starting or stopping norgestimate and adjust antidiabetic therapy if needed.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Linagliptin-metformin with Norgestimate?

MediHelp rates the interaction as minor. Linagliptin-metformin and Norgestimate have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Norgestimate-containing contraceptives can have a small effect on glucose tolerance. Significant loss of glycemic control is unlikely with modern low-dose products.

How serious is the interaction between Linagliptin-metformin and Norgestimate?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose after starting or stopping norgestimate and adjust antidiabetic therapy if needed.

What other medicines interact with Linagliptin-metformin?

MediHelp also lists interactions of Linagliptin-metformin with, for example, Apalutamide, Carbamazepine, Contrast media. The full list is on the Linagliptin-metformin page.

Full monographs, dosing and an interaction checker in the MediHelp app

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