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Drug interactions

Linagliptin-metformin + Progesterone micronized

Severity: Minor

Linagliptin-metformin and Progesterone micronized: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Oral micronized progesterone may modestly affect glucose tolerance in some patients, though clinically significant effects are uncommon.

What this interaction means in plain words

Linagliptin-metformin and Progesterone micronized have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Evidence level: Low

Why it happens

Progestogen-related mild insulin resistance may oppose antidiabetic effect.

What to do

Monitor blood glucose after starting or stopping progesterone and adjust antidiabetic therapy if control changes.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Linagliptin-metformin with Progesterone micronized?

MediHelp rates the interaction as minor. Linagliptin-metformin and Progesterone micronized have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Oral micronized progesterone may modestly affect glucose tolerance in some patients, though clinically significant effects are uncommon.

How serious is the interaction between Linagliptin-metformin and Progesterone micronized?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose after starting or stopping progesterone and adjust antidiabetic therapy if control changes.

What other medicines interact with Linagliptin-metformin?

MediHelp also lists interactions of Linagliptin-metformin with, for example, Apalutamide, Carbamazepine, Contrast media. The full list is on the Linagliptin-metformin page.

Full monographs, dosing and an interaction checker in the MediHelp app

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