Drug interactions
Linagliptin-metformin + Sage
Severity: Minor
Linagliptin-metformin and Sage: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Sage has shown glucose-lowering activity in experimental and small clinical studies, so it could add to the effect of metformin and linagliptin. Clinically significant hypoglycemia is unlikely.
What this interaction means in plain words
Linagliptin-metformin and Sage have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Theoretical additive glucose-lowering effect, possibly through improved insulin sensitivity.
What to do
Monitor blood glucose if sage is used medicinally and adjust antidiabetic therapy if readings fall.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Linagliptin-metformin
Frequently asked questions
Can I take Linagliptin-metformin with Sage?
MediHelp rates the interaction as minor. Linagliptin-metformin and Sage have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Sage has shown glucose-lowering activity in experimental and small clinical studies, so it could add to the effect of metformin and linagliptin. Clinically significant hypoglycemia is unlikely.
How serious is the interaction between Linagliptin-metformin and Sage?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose if sage is used medicinally and adjust antidiabetic therapy if readings fall.
What other medicines interact with Linagliptin-metformin?
MediHelp also lists interactions of Linagliptin-metformin with, for example, Apalutamide, Carbamazepine, Contrast media. The full list is on the Linagliptin-metformin page.
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