Drug interactions
Linezolid + Metaproterenol
Severity: Moderate
Linezolid and Metaproterenol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Metaproterenol is a beta-agonist whose cardiovascular effects may be potentiated by MAO inhibitors. Linezolid may therefore increase risk of tachycardia, arrhythmia and blood pressure changes.
What this interaction means in plain words
Linezolid and Metaproterenol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Pharmacodynamic potentiation of adrenergic effects through MAO inhibition.
What to do
Prefer inhaled therapy at the lowest effective dose and monitor heart rate and blood pressure. Consider another bronchodilator if cardiovascular effects appear.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Linezolid
- Amoxapine + Linezolid Contraindicated
- Atomoxetine + Linezolid Contraindicated
- Benzphetamine + Linezolid Contraindicated
- Brimonidine + Linezolid Contraindicated
- Bupropion-naltrexone + Linezolid Contraindicated
- Bupropion + Linezolid Contraindicated
Frequently asked questions
Can I take Linezolid with Metaproterenol?
MediHelp rates the interaction as moderate. Linezolid and Metaproterenol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Metaproterenol is a beta-agonist whose cardiovascular effects may be potentiated by MAO inhibitors. Linezolid may therefore increase risk of tachycardia, arrhythmia and blood pressure changes.
How serious is the interaction between Linezolid and Metaproterenol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Prefer inhaled therapy at the lowest effective dose and monitor heart rate and blood pressure. Consider another bronchodilator if cardiovascular effects appear.
What other medicines interact with Linezolid?
MediHelp also lists interactions of Linezolid with, for example, Amoxapine, Atomoxetine, Benzphetamine. The full list is on the Linezolid page.
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