Drug interactions
Lonapegsomatropin + Thioridazine
Severity: Minor
Lonapegsomatropin and Thioridazine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Growth hormone may increase the activity of some CYP450 enzymes, potentially lowering concentrations of drugs metabolized by them. Thioridazine is mainly metabolized by CYP2D6, so any effect is probably small and unproven.
What this interaction means in plain words
Lonapegsomatropin and Thioridazine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Lonapegsomatropin belongs to Endocrine; Thioridazine belongs to Central Nervous System.
Why it happens
Possible growth hormone-related induction of CYP450 metabolism; the effect on thioridazine is not established.
What to do
No routine action is needed; monitor clinical response and adverse effects if thioridazine dosing is stable and growth hormone is started or stopped.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Thioridazine
- Abiraterone + Thioridazine Contraindicated
- Adagrasib + Thioridazine Contraindicated
- Amiodarone + Thioridazine Contraindicated
- Amisulpride + Thioridazine Contraindicated
- Amitriptyline + Thioridazine Contraindicated
- Amoxapine + Thioridazine Contraindicated
Other interactions of Lonapegsomatropin
Frequently asked questions
Can I take Lonapegsomatropin with Thioridazine?
MediHelp rates the interaction as minor. Lonapegsomatropin and Thioridazine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Growth hormone may increase the activity of some CYP450 enzymes, potentially lowering concentrations of drugs metabolized by them. Thioridazine is mainly metabolized by CYP2D6, so any effect is probably small and unproven.
How serious is the interaction between Lonapegsomatropin and Thioridazine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine action is needed; monitor clinical response and adverse effects if thioridazine dosing is stable and growth hormone is started or stopped.
What other medicines interact with Thioridazine?
MediHelp also lists interactions of Thioridazine with, for example, Abiraterone, Adagrasib, Amiodarone. The full list is on the Thioridazine page.
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