Drug reference
thioridazine
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Central Nervous System (Anti Psychotic)
Mechanism of action
Piperazine phenothiazine agent; antagonist for the postsynaptic mesolimbic dopaminergic D2 receptors in the brain; decreases the release of hypothalamic and hypophyseal hormones
Common side effects
- Anticholinergic effects
- Sedation
- Akathisia
- Weight gain
- Dystonia
- Muscle stiffness
Known interactions (33)
- amiodarone + thioridazine Contraindicated
- amisulpride + thioridazine Contraindicated
- anagrelide + thioridazine Contraindicated
- aripiprazole + thioridazine Contraindicated
- asenapine + thioridazine Contraindicated
- buprenorphine + thioridazine Contraindicated
- clomipramine + thioridazine Contraindicated
- clozapine + thioridazine Contraindicated
- crizotinib + thioridazine Contraindicated
- degarelix + thioridazine Contraindicated
- donepezil + thioridazine Contraindicated
- dronedarone + thioridazine Contraindicated
- duloxetine + thioridazine Contraindicated
- escitalopram + thioridazine Contraindicated
- fingolimod + thioridazine Contraindicated
- fluoxetine + thioridazine Contraindicated
- fluvoxamine + thioridazine Contraindicated
- gemifloxacin + thioridazine Contraindicated
- hydroxyzine + thioridazine Contraindicated
- imipramine + thioridazine Contraindicated
- paroxetine + thioridazine Contraindicated
- alfuzosin + thioridazine Major
- atomoxetine + thioridazine Major
- cabergoline + thioridazine Major
- carvedilol + thioridazine Major
- darifenacin + thioridazine Major
- desipramine + thioridazine Major
- goserelin + thioridazine Major
- granisetron + thioridazine Major
- indapamide + thioridazine Major
- ipratropium-salbutamol + thioridazine Major
- isoflurane + thioridazine Major
- dopamine + thioridazine Moderate
Related conditions
Frequently asked questions
What drug class is thioridazine?
thioridazine belongs to: Central Nervous System.
How does thioridazine work?
Piperazine phenothiazine agent; antagonist for the postsynaptic mesolimbic dopaminergic D2 receptors in the brain; decreases the release of hypothalamic and hypophyseal hormones
What are the common side effects of thioridazine?
Anticholinergic effects, Sedation, Akathisia, Weight gain, Dystonia, Muscle stiffness
Which drugs interact with thioridazine?
amiodarone, amisulpride, anagrelide, aripiprazole, asenapine, buprenorphine, clomipramine, clozapine, crizotinib, degarelix, donepezil, dronedarone, duloxetine, escitalopram, fingolimod
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